ESPROGEN™

FEMALE HORMONESUPPORT FORMULA

BENEFITS

• reduce symptoms related to PMS  
• Improve menstrual regularity  
• Reduce menstrual cramps  
• Reduce hot flashes  
• Reduce menopausal moodiness

Angelica sinensis (Dong quai) is perhaps the best known phytoestrogen. It has been shown to be effective in the treatment of menstrual disorders, including irregular menses, premenstrual syndrome, endometriosis, fibroids and menopausal hot flashes through its alterative action on estrogen. Additionally, Angelica has been found to possess pain relieving and mild tranquilizing action. In one study, its pain relieving action was found to be greater than that of aspirin. Its pain relieving and smooth muscle relaxing actions support is historical use for uterine cramps and headaches.

Dioscorea villosa (Wild Yam ) contains progesterone precursors (diosgenin and pregnenolone) as well as anti-inflammatory and spasmolytic components that have been used to reduce the spasms associated with the cramping pain of menses, ovulation and afterpains following childbirth.

Glycyrrhiza glabra (Licorice root) is another phytoestrogen that exerts a balancing effect on estrogen metabolism. The estrogenic action of licorice is due to its isoflavone content. It appears to be extremely beneficial in relieving the symptoms of premenstrual syndrome (depression, craving sweets, weight gain, breast tenderness, etc.) due to its ability to balance the estrogen to progesterone ratio. Vital Formulations uses only DeGlycyrrhizinated Licorice (DGL) in its formula to prevent potassium loss.

Tunera diffusa (Damiana) has been found to bind to progesterone receptors and increase progesterone activity, while antagonizing cell growth of breast cancer cell lines.

Cimicifuga (Black Cohosh) has been shown in double-blind, placebo-controlled clinical trials to have significant benefit in treating both the physical and mental symptoms of premenstrual syndrome, juvenile menstrual disorders and menopause. In addition to phytoestrogens found in Cimicifuga, other plant constituents have been found to work via other mechanisms. Recently, a study concluded that at least three different compounds, including an estrogen-binding flavonoid, act synergistically to suppress lutenizing hormone (LH), which is considered to be an important initiating hormone for hot flashes in menopause. Unlike synthetic estrogens Cimicifuga does not alter Follicle Stimulating Hormone (FSH) levels or stimulate the growth of tumor cells. In several clinical trials, Cimicifuga has been shown to provide significant improvement in 86% of all patients within 4 weeks of onset of therapy. Studies show that Cimicifuga reduces menopausal symptoms of hot flashes, perspiration, headache, vertigo, heart palpitations, ringing in the ears, nervousness, irritability, sleep disturbances, weariness, and depressive moodiness, while increasing motivation and mood.